Products and Services

MDM develops medical decision models that are based on the research, interpretation, compilation, and incorporation of data and algorithms from a variety of scientifically-defensible sources. These sources include clinical trial, healthcare claims, epidemiological, and market data; and published meta-analyses and decision models from peer-reviewed medical journals. A key characteristic of all MDM-developed models is their flexibility to allow modifications of input data and assumptions related to effectiveness, costs, and population demographics. This allows the models to be credibly utilized both by marketers of pharmaceutical products and medical devices, as well as by their potential customers.

MDM specializes in the development of budget impact, cost-effectiveness, and disease progression models. Specifically, MDM is a leader in the development of healthcare-related discrete-event and microsimulation models utilizing its decades of engineering experience. MDM's model outputs typically include estimates of treatment and disease costs, market size and market share of these treatment, patient life expectancy (both with and without quality-adjustment), complication and mortality rates, and numerous cost-effectiveness measures. Depending on the requirements of the user, the decision models will output data for specified heterogeneous or homogeneous populations of patients as well as for individual patients.

MDM develops and updates dossiers for formulary submission for new and currently approved medical device and pharmaceutical products, including Academy of Managed Care Pharmacy (AMCP) Formulary Submission Dossiers, National Institute for Health and Clinical Excellence (NICE) dossiers, Australia national formulary dossiers, dossiers for the Candian Agency for Drugs and Technologies in Health, and dossiers for the European Commission. MDM's pharmaceutical profile documents typically incorporate information from key clinical trials and economic studies, data from the current published prescribing information, an adverse event profile, a rigorous disease-state description, an overview on related budget impact models and cost effectiveness analysis, and an overall product value assessment. MDM has extensive experience developing budget impact and cost-effect analysis models in conjunction with dossier projects.